August 26th, 2019 The new SARRP beamline pre-clinical radiation research and CT imaging platform launched at the Xstrahl booth at ICRR in Manchester, UK, August 25th-29th Xstrahl Life Science, global leader in the development of advanced X–ray systems for pre-clinical...
August 26th, 2019 Xstrahl Life Science, global leader in advanced radiation research systems, is introducing a Monte Carlo dose engine to enable comparative research work to be carried out on its Small Animal Radiation Research Platform (SARRP) system. The new...
Small animal radiotherapy research platforms such as Xstrahl's SARRP enable more precise irradiation of tumours and normal tissues in pre-clinical models of cancer. In their study “Evaluation of four different small animal radiation plans on tumour and normal tissue...
In their paper “Interleukin 6 Signaling Blockade Exacerbates Acute and Late Injury From Focal Intestinal Irradiation” Bell BI, Koduri S, Salas Salinas C, et al, aim to evaluate the acute changes in leukocyte populations after focal irradiation and to assess the role...
Radiotherapy is recognized as one of the main modalities for the treatment of cancer in the world, the translation of the results of the pre-clinical research to clinical trials represents an optimization of the resources destined to combat this disease. Improvements...
Meningiomas are a frequent tumor of the central nervous system. Although mostly benign, approximately 5% present as atypical or malignant tumors. Treatments for atypical meningiomas include gross total resection and radiotherapy, but about 33% of patients have...
Craniospinal irradiation (CSI) is a crucial component of treatment for medulloblastoma (MB), a brain tumor clinically stratified into prognostically distinct molecular subgroups. Preclinical models of clinically relevant CSI offer the potential to study radiation dose...
Tumor hypoxia reduces the effectiveness of radiation therapy by limiting the biologically effective dose. An acute increase in tumor oxygenation before radiation treatment should therefore significantly improve the tumor cell kill after radiation. Efforts to increase...
Inhibition of ataxia-telangiectasia mutated (ATM) during radiotherapy of glioblastoma multiforme (GBM) may improve tumor control by short-circuiting the response to radiation-induced DNA damage. A major impediment for clinical treatment is that current inhibitors have...
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