BACKGROUND AND PURPOSE: High-precision radiotherapy (RT) requires precise positioning, particularly with high single doses. Fiducial markers in combination with onboard imaging are excellent tools to support this. The purpose of this study is to establish a pancreatic...
Despite both clinical and pre-clinical technological advancements, a lack of effective treatment for patients with primary brain tumors and those originating from metastasis remains. With the 5-year survival rate of patients experiencing primary glioblastoma...
The development of image-guided small animal irradiators represents a significant improvement over standard irradiators by enabling preclinical studies to mimic radiotherapy in humans. The ability to deliver tightly collimated targeted beams, in conjunction with...
To recommend imaging protocols and establish tolerance levels for microCT image quality assurance (QA) performed on conformal image-guided small animal irradiators. A fully automated QA software SAPA (small animal phantom analyzer) for image analysis of the commercial...
The mission of most cancer centers, in some shape or form, is to contribute to the prevention and cure of cancer. To accomplish such a mission, a large focus must be placed on research in both the clinical and pre-clinical laboratory setting. In order to yield...
Purpose/Objective To establish a novel preclinical model for stereotactic radiosurgery with combined mouse-like phantom quality assurance in the setting of brain metastases. Material Methods C57B6 mice underwent intracranial injection of B16-F10 melanoma cells....
The SARRP User Spring Symposium event gathers together thought leaders, scholars and operators of Xstrahl Small Animal Radiation Research (SARRP) systems from all over the world.
The development and construction of clinical proton therapy centers has almost become the norm for any major cancer treatment center. Roughly 58 proton centers are currently operating throughout the world, and an estimated 52 (this number could be greater) are currently being built or are planned for construction. With the recent emergence of so many proton centers more so than ever, one would think the use of protons in cancer is a new form of treatment. However, the truth of the matter is it’s basically the opposite.
Background and Purpose: Currently, no readily available mitigators exist for acute abdominal radiation injury. Here, we present an animal model for precise and homogenous limb-sparing abdominal irradiation (LSAIR) to study the radiation-induced gastrointestinal...
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