Xstrahl in Action This paper describes the use and dosimetric validation of a newly developed Monte Carlo (MC) tool, SmART-RAD, to simulate the X-ray field in a range of standard commercial X-ray cabinet irradiators used for preclinical irradiations. Comparisons are...
See what researchers found in the recent study: Enhancement of antitumor immune response by radiation therapy combined with dual immune checkpoint inhibitor in a metastatic model of HER2‑positive murine tumor. See the original publication here.
In the recent study, Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation, researchers found that a dose reduction is necessary for X-rays to achieve comparable biological effects. See more below and the original study here....
The extent of tumor oxygenation is an important factor contributing to the efficacy of radiation therapy. Several preclinical studies have shown benefit of combining radiation therapy with drugs that inhibit tumor blood vessel growth, i.e. angiostatic therapy. Recent...
Current treatment methods for arteriovenous malformation (AVM) are surgery and radiosurgery. However, complete occlusion post radiosurgery is achieved within 3 years, while patient remain at risk of haemorrhage. Therefore is important to develop a new molecular...
For the last 12 years the CIX3 irradiator cabinet has been a stable of cancer research centres around the world. With demand high, Xstrahl spent 2 years developing a new generation of the system, with reduced footprint, safer controls, larger irradiation chamber and...
Chemotherapy and Radiotherapy utilize DNA-PK and PARP inhibitors to sensitize cancer cells, however these inhibitors have so far only been limited to homologous recombination repair deficient tumors, exploiting synthetic lethality. In the study “Sensitizing ewing...
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