Tumor hypoxia is a common feature of prostate tumors associated with the stabilization of hypoxia-inducible-factor 1alpha (HIF-1α) and poor prognosis following radiation therapy. Lack of oxygen at the time of irradiation is associated with radioresistance, but recent reports suggest radioresponse is also modulated by the dynamic nature of tumor hypoxia.
Derek Hennessey, Lynn Martin, Anne Atzberger, Thomas Lynch, Donal Hollywood and Laure Marignol
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SPOTLIGHT: Translating and Optimizing Experimental Design from Caesium to X-Ray Based Irradiators
SPOTLIGHT: Translating and Optimizing Experimental Design from Caesium to X-Ray Based Irradiators Transitioning your lab’s irradiation capabilities is a significant undertaking. The primary concern for any researcher making the switch from Caesium to X-ray is...
