…irradiator such as SARRP. As in the clinic, additional imaging and identification techniques can be adopted for increased targeting accuracy. Furthermore, it sheds light on curcumin, something to be considered…
…image-guided radiotherapy (IGRT) is a common practice to help clinicians accurately target tumors located within the abdominal area. Tumors located in areas such as the gastrointestinal tract, pancreas, and liver…
Modulation of the redox system in cancer cells has been considered a promising target for anti-cancer therapy. The novel MTH1 inhibitor TH588 proved tremendous potential in terms of cancer cell…
…and by other DNA damaging targets (Vanpouille-Box et al.) As much as the scientific community and world population would like there to be a silver bullet to cure all cancer,…
Although glucocorticoids (GCs) are a mainstay in the clinical management of asthma, the target cells that mediate their therapeutic effects are unknown. Contrary to our expectation, we found that GC…
…The team then compared these physical results against a “validated MC model of the SARRP system” and concluded that, for each treatment variation and target, “the mean dose deviation between…
…MSE) to identify and quantify membrane protein expression at various time-points following irradiation which simulates a radiosurgical treatment approach. Immunocytochemistry was used to confirm the expression of selected membrane proteins….
Dr. Costas Koumenis, PhD, Professor and Vice-Chair for Research, at the University of Pennsylvania The University of Pennsylvania (UPenn) was an early adopter of SARRP, acquiring a system in 2011…
The purpose of this work is to determine, using Monte Carlo simulation and a realistic patient model, the characteristics of the resultant absorbed dose distributions when breast tumors are irradiated…
…Inspiring Science & Research The Small Animal Radiation Research Platform (SARRP) is the most advanced 3D-image guided micro irradiator that’s commercially available and serves as Xstrahl’s flagship research system. SARRP…