Hypoxia response element-driven cytosine deaminase/5-fluorocytosine gene therapy system: a highly effective approach to overcome the dynamics of tumour hypoxia and enhance the radiosensitivity of prostate cancer cells in vitro.

I have spent more than twenty years in radiation therapy, building systems, advising clinicians, and working to bring this technology to more patients. Last year, I became one of those patients myself. Diagnosed with Dupuytren’s contracture, I went through two rounds of low-dose radiation treatment at the same kind of facility I have spent my career supplying. What followed was one of the most clarifying professional experiences of my life, and a reminder that the gap between understanding a treatment and actually receiving one is wider than most people inside this industry ever appreciate.