Xstrahl in Action The efficacy and side effects of radiotherapy (RT) depend on parameters like dose and the volume of irradiated tissue. RT induces modulations of the tumor immune microenvironment (TIME) that are dependent on the dose. Low dose RT (LDRT, i.e., single...
Xstrahl in Action Studies during the past 9 years suggest that delivering radiation at dose rates exceeding 40 Gy/s, known as “FLASH” radiation therapy, enhances the therapeutic index of radiation therapy (RT) by decreasing normal tissue damage while maintaining tumor...
Xstrahl in Action Advances in conformal radiotherapy (RT) techniques and image-guidance have significantly reduced organs at risk (OAR) exposure, which has been associated with improved safety profiles. However, opportunities remain to further optimise treatments...
Xstrahl in Action In radiology, low X-ray energies (<140 keV) are used to obtain an optimal image while in radiotherapy, higher X-ray energies (MeV) are used to eradicate tumor tissue. In radiation research, both these X-ray energies are being used to extrapolate...
Xstrahl in Action This paper describes the use and dosimetric validation of a newly developed Monte Carlo (MC) tool, SmART-RAD, to simulate the X-ray field in a range of standard commercial X-ray cabinet irradiators used for preclinical irradiations. Comparisons are...
Xstrahl in Action Researchers developed guidance on how and what to report in regard to dosimetry in radiation research.Publication Minimum reporting standards should be expected for preclinical radiobiology irradiators and dosimetryAuthors François Trompier, Larry A....
Xstrahl in Action Pelvic radiotherapy (RT) can cause debilitating bladder toxicities. In the recent study, researchers sought methods to protect against and alleviate RT-induced late bladder injury.Publication Prevention of radiation-induced bladder injury: A murine...
Xstrahl in Action A recent study aimed to characterize a detection system based on inorganic scintillators and determine its suitability for dosimetry in preclinical radiation research, using our Small Animal Radiation Research Platform (SARRP).Publication...
Researchers sought to understand the role of kV treatment in locally advanced and/or metastatic breast cancer in which kV radiotherapy was used as the primary modality or as supportive treatment to linac-based RT to gain local tumor control and improve the patient’s quality of life. See details of the recent study, Kilovoltage radiotherapy as a supportive treatment in locally advanced or metastatic breast cancer – a series of six case reports, and the full report on six cases.
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