Xstrahl in Action This paper describes the use and dosimetric validation of a newly developed Monte Carlo (MC) tool, SmART-RAD, to simulate the X-ray field in a range of standard…
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Priming the Abscopal Effect Using Multifunctional Smart Radiotherapy Biomaterials Loaded with Immunoadjuvants
In this study, we investigate the use of multifunctional smart radiotherapy biomaterials (SRBs) loaded with immunoadjuvants for boosting the abscopal effect of local radiotherapy (RT). SRBs were designed similar to…
Multi-institutional MicroCT image comparison of image-guided small animal irradiators
…commercial PXi X-RAD SmART and Xstrahl SARRP systems) with varying parameters used for routine small animal imaging were analyzed. Multi-institutional data sets were compared using SAPA, based on which tolerance…
Enhancing the Therapeutic Efficacy of Cancer Treatment With Cannabinoids.
…leverage these effects in clinical translation. This study explores the potential of combination approaches employing CBDs with radiotherapy (RT) or smart biomaterials toward enhancing therapeutic efficacy during treatment of pancreatic…
An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse
Introduction Preclinical CT-guided radiotherapy platforms are increasingly used but the CT images are characterized by poor soft tissue contrast. The aim of this study was to develop a robust and…
MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform
…A, Falzone N, Kersemans V, Thompson J, Hill M, Allen PD, Beech J, Gilchrist S, Kinchesh P, Vojnovic B, Tullis I, Gaze MN, Smart S & Vallis KA. Download Paper…
The Development of Technology for Effective Respiratory-Gated Irradiation Using an Image-Guided Small Animal Irradiator
…breathing related movement is significant. Hill MA, Thompson JM, Kavanagh A, Tullis IDC, Newman RG, Prentice J, Beech J, Gilchrist S, Smart S, Fokas E & Vojnovic B. Download Paper…