…use of SARRP. This study was able to mimic the radiation treatment used in a clinical setting and minimize radiation toxicity or damage to surrounding tissues. See the full details…
…collimator made it possible to adjust the treatment beam size to each mouse. The preclinical results have led to a phase 1 clinical study. See more from Dr. Wilson’s and…
Neuroblastoma has one of the lowest survival rates of all childhood cancers despite the use of intensive treatment regimens usually consisting of a mix of surgery, chemotherapy, radiotherapy, stem cell…
…dose computation has been integrated into the treatment planning system for SARRP. In their paper “Validation of GPU-accelerated superposition-convolution dose computations for the Small Animal Radiation Research Platform” Cho N,…
…Research Platform (SARRP) to deliver radiation to precise fields equivalent to clinical practice, allowing us to investigate systemic versus targeted damage in a structure as small as the mouse ovary….
…standard (mouse standing on couch) imaging geometries for 40-80 kVp tube voltages. Imaging dose for off-center positioning shifts and maintaining image noise across tube voltages were also calculated. Half-value layer…
…lung is an efficient model for long-term studies. However, irradiation may have a strong impact on the structure and function of neighboring organs, which must be considered. HIF-1α conditional deletion…
In this study, Development and Implementation of an End-To-End Test for Absolute Dose Verification of Small Animal Preclinical Irradiation, SARRP data was collected from SARRP systems across five institutions to…
…Urs, PhD, Senior Scientist, Scientific Development, Labcorp, described how SARRP was used to evaluate the tumor model’s sensitivity to radiation. The study found dose-dependent tumor regression from single radiation treatments….
See what researchers found in the recent study: Enhancement of antitumor immune response by radiation therapy combined with dual immune checkpoint inhibitor in a metastatic model of HER2‑positive murine tumor….