Patients with glioblastoma have poor outcomes due to local relapse despite surgery and high-dose radiotherapy. Resistance to radiotherapy is thought to be due to efficiency of DNA repair cells, such…
…locoregional relapse and/or metastatic disease following RT. The use of immunotherapy in non–small-cell lung cancer (NSCLC) could potentially change this outcome by enhancing the effects of RT. Here, we report…
…as well. SARRP is used by academic research institutions, private contract research organizations, and pharmaceutical and biotech companies worldwide, showing a wide range of research interests. The Radiation Research Community…
In the recent publication, Zebrafish as an in vivo screening tool to establish PARP inhibitor efficacy, researchers examined treatment modalities to aid the development of PARP inhibitors. These compounds target…
PURPOSE: We aimed to characterise magnetic nanoparticle hyperthermia (mNPH) with radiation therapy (RT) for prostate cancer. METHODS: Human prostate cancer subcutaneous tumours, PC3 and LAPC-4, were grown in nude male…
…Radiation Research Platform, helping to target your preclinical research. We hope that you all have a chance to meet us in Milan, and see what Xstrahl can do for you….
…Point dose measurements obtained with the PSD were similarly compared for each of the candidate (brain, abdomen, and tumor) treatment sites. RESULTS: For each treatment configuration and anatomical target, the…
…observed outside the target volume were attributed to non-targeted effects and showed no dependence on either MLD or V10. CONCLUSIONS: Quantitative assessment of normal tissue response closely correlates early and…
PURPOSE: To develop and test the suitability and performance of a comprehensive quality assurance (QA) phantom for the Small Animal Radiation Research Platform (SARRP). METHODS AND MATERIALS: A QA phantom…
…effector target genes. Nonetheless, glucose restriction is sufficient to suppress Atg5-dependent increases in effector function. Thus, autophagy-dependent changes in CD8+ T cell metabolism directly regulate anti-tumor immunity. DeVorkin L, Pavey…