In the recent publication, Zebrafish as an in vivo screening tool to establish PARP inhibitor efficacy, researchers examined treatment modalities to aid the development of PARP inhibitors. These compounds target tumors deficient in the Homologous Recombination pathway, which are associated with increased risk for breast, ovarian, pancreatic and prostate cancer.
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While SARRP is often used to investigate the effect of radiation therapy in preclinical oncology settings, it should be noted that the impact of radiation on normal tissues requires understanding and further research to mitigate both early and late effects. The use of...
Accurate dosimetry and reporting is the best practice in radiation research. While systems like the Xstrahl CIX series have been established as both reproducible and accurate, determining the exact dose delivered to a subject can be difficult due to the interactions...
Xstrahl in Action Researchers developed guidance on how and what to report in regard to dosimetry in radiation research.Publication Minimum reporting standards should be expected for preclinical radiobiology irradiators and dosimetryAuthors François Trompier, Larry A....
