…contrast agent, which enhances the lateral ventricles. T2-weighted MRI images were also used for target localization. Visualization of delivered beams (10 Gy) in tissue was accomplished with immunohistochemical staining for…
…X-ray radiation was delivered by using a Small Animal Radiation Research Platform (SARRP) with CT guided imaging that can accurately target lesions. Mice received a single dose of 10 Gy…
The Small Animal Radiation Research Platform (SARRP) is a novel isocentric irradiation system that enables state-of-the-art image-guided radiotherapy research to be performed with animal models. This paper reports the results…
…associated with such devices. Integrating the irradiation chamber and system electronics within a single enclosure, radiation is delivered using two X-ray tubes (one positioned on the top and one on…
The radiopharmaceutical (131)I-meta-iodobenzylguanidine ((131)I-MIBG) is an effective treatment for neuroblastoma. However, maximal therapeutic benefit from (131)I-MIBG is likely to be obtained by its combination with chemotherapy. In a previous paper…
…important to develop a new molecular targeted treatment for the brain, by identification of membrane proteins that are localised on the AVM endothelium. In their study “Identification of protein targets…
…modulated radiation fields or spatially fractionated treatments such as spatially fractionated radiotherapy (GRID). METHODS: Using the small-animal radiotherapy research platform as a key enabling technology to deliver precision imaged-guided radiotherapy,…
…Mouse Bed 4D Treatment Head WATCH OUR SARRP SERIES Small Animal Radiation Research Platform SARRP is a customizable and powerful research platform designed to provide the preclinical research community with…
…organ-of-interest (target) is a major clinical concern. Ultra-small, renal clearable, silica based gadolinium chelated nanoparticles (SiGdNP) provide simultaneous MR contrast and radiation dose enhancement. The high atomic number of gadolinium…
…chamber, a filter changer, and a rapid response gating system. Compatible with both the variable collimators and micro collimators. SARRP has been developed to match the standard of care for…