…as RAD51, are able to survive DNA damage from radiotherapy and repopulate the tumour post treatment. Using Xstrahl’s SARRP, Harry King et al. used clinical patient derived glioblastoma stem cells…
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Prevention of Radiation-Induced Bladder Injury
Xstrahl in Action Pelvic radiotherapy (RT) can cause debilitating bladder toxicities. In the recent study, researchers sought methods to protect against and alleviate RT-induced late bladder injury. Publication Prevention of…
Xstrahl 200 Enables Gold Nanoparticle Research
…influence of the size and localization of gold nanoparticles on the dose increase factor. At the moment, on the basis of Moscow oncology hospital No. 62 studies on the influence…
DNA Damage Response (DDR) in Peripheral Blood Lymphocytes after Exposure to X-rays with Different Physical Properties
…physical parameters in radiation-related studies. The Value of SARRP Researchers used Xstrahl’s SARRP to irradiate cell cultures and determine if DDR in PBLs is influenced by the beam quality, MPE,…
Xstrahl in Action: Identification of protein targets for AVM molecular therapies
Current treatment methods for arteriovenous malformation (AVM) are surgery and radiosurgery. However, complete occlusion post radiosurgery is achieved within 3 years, while patient remain at risk of haemorrhage. Therefore is…
Xstrahl in Action: Model for Precise and Uniform Pelvic- and Limb-Sparing Abdominal Irradiation For Study
…radiation-induced gastrointestinal syndrome and the development of potential medical countermeasures to mitigate the effects of radiation exposure Brodin N.P., Velcich A., Guha C and Tomé W.A. in their study “A…
Inorganic Scintillator Detectors for Dosimetry in Image-Guided Small Animal Radiotherapy
…The methodology for cross-calibration contributes to the development of end-to-end tests to achieve independent dosimetry verification of RT plans delivered by image-guided small animal irradiation platforms. The development of in-vivo…
Xstrahl in Action: Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation
…about radiobiological mechanisms underlying this clinical successful LD-RT application. The objective of the study “Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation: Cytokine Release of Murine Endothelial Cells Is Dependent…
Xstrahl in Action: Dosimetric characterization of a single crystal diamond detector in X-ray beams
…film has a steeper dose gradient in the penumbra region but also a higher noise than the microDiamond detector. They demonstrated that the microDiamond detector is a useful measurement tool…
Xstrahl in Action: SARRP Helps Research Team Validate Success of New Proton FLASH RT System
…“employed custom 3-dimensional printed jigs with anesthesia gas ports” to work directly with the mice. The SARRP platform provides the fundamental, pre-clinical environment necessary to configuring a highly targeted experiment…