In preclinical radiation research, it is challenging to localize soft tissue targets based on cone beam computed tomography (CBCT) guidance. As a more effective method to localize soft tissue targets, we developed an online bioluminescence tomography (BLT) system for small-animal radiation research platform (SARRP). We demonstrated BLT-guided radiation therapy and validated targeting accuracy based on a newly developed reconstruction algorithm.
Zhang B, Wang KK, Yu J, Eslami S, Iordachita I, Reyes J, Malek R, Tran PT, Patterson MS, Wong JW.
Prevention of Radiation-Induced Bladder Injury
Pelvic radiotherapy (RT) can cause debilitating bladder toxicities. In the recent study, Prevention of Radiation-Induced Bladder Injury: A Murine Study Using Captopril, researchers sought methods to protect against and alleviate RT-induced late bladder injury. See details and the full study here.