Significant improvements in radiotherapy are likely to come from biological rather than technical optimization, for example increasing tumour radiosensitivity via combination with targeted therapies. Such paradigms must first be evaluated in preclinical models for...
In their paper “Effect of X-ray minibeam radiation therapy on clonogenic survival of glioma cells.” Guardiola C, Prezado Y, Roulin C, Bergs JWJ report on the first in vitro study performed in an X-ray Small Animal Radiation Research Platform (SARRP) modified for...
13th June, 2019 Xstrahl Spotlights Full Range of X-Ray Therapy and Radiation Research Systems at DEGRO 2019, June 13-16th Company also announces launch of patient-focused, German-language website providing information on treatment options for a range of benign...
Radiation exposure is known to cause accelerated aging and damage to the ovary, but the contribution of indirect versus direct effects is not well understood. In their paper “Use of a Small Animal Radiation Research Platform (SARRP) facilitates analysis of systemic...
In the prostate, stem and progenitor cell regenerative capacities have been ascribed to both basal and luminal epithelial cells. Here, we show that a rare subset of mesenchymal cells in the prostate are epithelial-primed Nestin-expressing cells (EPNECs) that can...
Xstrahl is pleased to be invited as a sponsor to the 16th International Tumor Microenvironment Workshop taking place between Thursday 13th June through Saturday 15th June in Miami Beach, Florida. Cancer is a complex and heterogeneous disease involving the interaction...
Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and the fastest growing malignancy in the United States. With a 5-year survival rate below 12%, effective therapies for HCC are needed. Current treatments for HCC include microwave...
OBJECTIVES: Hypoxic cancer cells have been shown to be more resistant to radiation therapy than normoxic cells. Hence, this study investigated whether ultrasound (US)-induced rupture of oxygen-carrying microbubbles (MBs) would enhance the response of breast cancer...
DNA-damaging chemotherapy and radiation therapy are integrated into the treatment paradigm of the majority of cancer patients. Recently, immunotherapy that targets the immunosuppressive interaction between programmed death 1 (PD-1) and its ligand PD-L1 has been...
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