OBJECTIVE Non-ablative or mild hyperthermia (HT) has been shown in preclinical (and clinical) studies as a localized radiosensitizer that enhances the tumoricidal effects of radiation. Most preclinical in vivo HT studies use subcutaneous tumor models which do not...
February 28th, 2019 – Xstrahl Medical, global leader in superficial radiotherapy devices to treat non-melanoma skin cancer and dermatological conditions, is spotlighting its RADiant treatment system at the American Academy of Dermatology (AAD) annual meeting in...
In their study “Improved Overall Survival of Mice by Reducing Lung Side Effects After High-Precision Heart Irradiation Using a Small Animal Radiation Research Platform” Sievert W, Stangl S, Steiger K, Multhoff G aim to reduce radiation exposure of the lung in...
The orthovoltage x-ray energy frequently used in radiation research is prone to dosimetry errors due to insufficient backscatter conditions. In many radiobiology studies, especially for cell irradiations, precise dose calculation algorithms such as...
February 20th, 2019 – Xstrahl Medical, global leader in superficial radiotherapy devices and advanced radiation research systems, is celebrating 20 years of delivering technical training courses on its X-ray treatment systems. The courses are conducted several times...
In their study “MicroCT imaging dose to mouse organs using a validated Monte Carlo model of the small animal radiation research platform (SARRP)” Johnstone CD and Bazalova-Carter M, establish imaging dose to mouse organs with a validated Monte Carlo (MC) model of the...
Binding of the apolipoprotein E (ApoE)-containing lipoprotein complex to the low-density lipoprotein receptor (LDLR) is essential for cholesterol and lipid homeostasis. Inherited abnormalities in ApoE or LDLR function result in early onset cardiovascular disease and...
February 6th, 2019 – A leading dermatology center in Tennessee has commenced advanced skin radiotherapy treatments using the new RADiant treatment system from Xstrahl Medical, global leader in superficial radiotherapy devices to treat non-melanoma skin cancer and...
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic stroma with a poor lymphocyte infiltrate, in part driven by cancer-associated fibroblasts (CAFs). CAFs, which express fibroblast activation protein (FAP), contribute to immune escape via exclusion...
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