Bladder drug delivery via catheter instillation is a widely used treatment for recurrence of superficial bladder cancer. Intravesical instillation of liposomal botulinum toxin has recently shown promise in the treatment of overactive bladder and interstitial cystitis/bladder pain syndrome, and studies of liposomal tacrolimus instillations show promise in the treatment of hemorrhagic cystitis. Liposomes are lipid vesicles composed of phospholipid bilayers surrounding an aqueous core that can encapsulate hydrophilic and hydrophobic drug molecules to be delivered to cells via endocytosis. This review will present new developments on instillations of liposomes and liposome-encapsulated drugs into the urinary bladder for treating lower urinary tract dysfunction.
Joseph J. Janicki, Michael B. Chancellor,* Jonathan Kaufman, Michele A. Gruber, and David D. Chancellor
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Bringing Superficial Radiation Therapy into Your Dermatology Practice: A Personal Journey
Xstrahl, a global leader in the delivery of superficial and orthovoltage radiation therapy and preclinical radiation research systems, will feature Radiant™ Aura with XBeam treatment planning at the annual meeting of the American Academy of Dermatology (AAD), in Orlando, FL, from March 7-9, 2025 (Booth #2975).
