Apart from the platelet/endothelial cell adhesion molecule 1 (PECAM-1, CD31), endoglin (CD105) and a positive factor VIII-related antigen staining, human primary and immortalized macro- and microvascular endothelial cells (ECs) differ in their cell surface expression of activating and inhibitory ligands for natural killer (NK) cells. Here we comparatively study the effects of irradiation on the phenotype of ECs and their interaction with resting and activated NK cells.
Isabelle Riederer, Wolfgang Sievert, Günther Eissner, Michael Molls and Gabriele Multhoff
SARRP Used in Salivary Gland Radiation Research
In the recent study, Short-term and bystander effects of radiation on murine submandibular glands, researchers sought to understand hyposalivation effects that can be caused by radiation. See details below and the full study here.