To present a novel method of tumor radiosensitization through Hsp27 knockdown using locked nucleic acid (LNA) and to investigate the role of Hsp27 in DNA double strand break (DSB) repair.
David M. Guttmann, Lori Hart, Kevin Du, Andrew Seletsky, Constantinos Koumenis
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Prevention of Radiation-Induced Bladder Injury
Pelvic radiotherapy (RT) can cause debilitating bladder toxicities. In the recent study, Prevention of Radiation-Induced Bladder Injury: A Murine Study Using Captopril, researchers sought methods to protect against and alleviate RT-induced late bladder injury. See details and the full study here.