Tumor hypoxia is a common feature of prostate tumors associated with the stabilization of hypoxia-inducible-factor 1alpha (HIF-1α) and poor prognosis following radiation therapy. Lack of oxygen at the time of irradiation is associated with radioresistance, but recent reports suggest radioresponse is also modulated by the dynamic nature of tumor hypoxia.
Derek Hennessey, Lynn Martin, Anne Atzberger, Thomas Lynch, Donal Hollywood and Laure Marignol
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Benign Radiotherapy 101
Radiation therapy is widely known for its role in treating cancer, but its benefits extend far beyond oncology. Low and intermediate doses of radiation therapy have a long and proven history in managing benign indications, particularly for hyperproliferative,...
