The microenvironment plays an important role in regulating tumor response to radiotherapy. Ionizing radiation can disrupt tumor vasculature, and Notch pathway inhibition can interfere with functional angiogenesis. We explored the potential cooperativity between Notch inhibition and ionizing radiation in delaying tumor growth.
Stanley K Liu, Saif A S Bham, Emmanouil Fokas, John Beech, Jaehong Im, Song Cho, Adrian L Harris and Ruth J Muschel
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SPOTLIGHT: Characterization and Biological Validation of Photon FLASH
SPOTLIGHT: Characterization and Biological Validation of Photon FLASH FLASH (Ultra-High Dose Rate) Radiotherapy is an emerging cancer treatment modality that delivers radiation doses in milliseconds rather than minutes with a significant reduction in healthy tissue...
