Throughout the last 100 years, numerous milestones in the study and treatment of cancer have been achieved. Discoveries like combination chemotherapy, correlation of smoking and lung cancer, HPV and cervical carcinogenesis, BRCA-1&2 gene inheritance and breast...
With skin cancer being the most common type of cancer in the USA the need for an effective and versatile treatment method is a necessity for many skin cancer centers. The Xstrahl 100 is perfectly suited for the treatment of superficial skin cancers, as used by the...
BACKGROUND: Preclinical radiation biology has become increasingly sophisticated due to the implementation of advanced small animal image guided radiation platforms into laboratory investigation. These small animal radiotherapy devices enable state-of-the-art image...
The consequences of low to moderate doses of ionizing radiation (IR), especially for children exposed to CT scans, remains a challenging scientific topic. So far, no proper experimental models are available to better comprehend the consequences of exposure of the...
Non-melanoma skin cancers (NMSC) are the most commonly diagnosed cancers in the world. Despite their relatively low malignant potential and mortality rate, NMSC are associated with a high morbidity and substantial treatment cost, and they significantly affect patient...
Radiotherapy (RT) enhances innate and adaptive antitumor immunity; however, the effects of radiation on suppressive immune cells, such as regulatory T cells (Treg), in the tumor microenvironment (TME) are not fully elucidated. Although previous reports suggest an...
Neuroblastoma has one of the lowest survival rates of all childhood cancers despite the use of intensive treatment regimens usually consisting of a mix of surgery, chemotherapy, radiotherapy, stem cell transplant, immunotherapy and retinoid therapy. However, because...
A novel RADiant system provides a pain free, non-surgical alternative for the treatment of non-melanoma skin cancer and superficial keloid lesions. The Xstrahl (Camberley, United Kingdom) RADiant System is a mobile, compact, ergonomic superficial X-ray therapy...
At the 2017 Annual Meeting of the American Society for Radiation Oncology (ASTRO) researchers announced the development of an efficient and reproducible method to deliver craniospinal irradiation to patient-derived xenograft in mouse models. Despite aggressive...
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