In this study, Beam Size Limit for Pencil Minibeam Radiotherapy Determined from Side Effects in an In-Vivo Mouse Ear Model, SARRP enabled researchers to utilize single minibeam irradiation, down to 0.5mm in diameter, along with adaptable beam energy and filtration....
SARRP, an image-guided small animal proton and x-ray research system, enables in vivo investigations of radiobiological effects of proton beams and comparative studies between proton and x-ray beams. This is the first system capable of delivering SOBP from a cyclotron...
In this video, Merle Reinhart, one of our SARRP experts, demonstrates the precision guided irradiation workflow in MuriPlan, SARRP's treatment planning system. She uses an example of brain irradiation to show how to design a treatment plan, including contouring and...
In this study, Radiation Cystitis Modeling a Comparative Study of Bladder Fibrosis Radio-Sensitivity in C57BL6, C3H, and Balb/c Mice, researchers attributed the strength and uniqueness of their approach to the use of SARRP. This study was able to mimic the radiation...
In this study, Development and Implementation of an End-To-End Test for Absolute Dose Verification of Small Animal Preclinical Irradiation, SARRP data was collected from SARRP systems across five institutions to help in developing this independent, traceable,...
In the study, Minibeam Radiation Therapy at a Conventional Irradiator: Dose-Calculation Engine and First Tumor-Bearing Animals Irradiation, SARRP was modified for MBRT experiments. Researchers had the chance to conduct systematic and comprehensive radiobiological...
In the study, In Vivo Bioluminescence Tomography-Guided Radiation Research Platform for Pancreatic Cancer: An Initial Study Using Subcutaneous and Orthotopic Pancreatic Tumor Models, investigation on subcutaneous and orthotopic models displayed the significance of...
Microbeam radiation is typically only available at large synchrotron facilities. SARRP brings this research into a regular laboratory, enabling researchers to study open physics and biology questions in this emerging field. See the results of this study, Evaluation of...
Nasal function and cosmesis are important considerations in the quality of life for nasal ala skin cancer patients. Surgery involves tissue loss, which is likely to lead to impaired function and undesired cosmetic results. Superficial radiotherapy can be an effective...
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