Area of Interest: Radiation Research
Cancer is a complex disease, with a variety of approaches available for its treatment. Treatment modalities are often combined to maximize response and to overcome the limitations of individual modalities when used alone. One such example is the combination of...
On January 29 - 30 the Nuclear Threat Initiative (NTI) together with the University of California and National Nuclear Security Administration (NNSA) held technical discussions on radiological risks associated with using cesium-137 irradiators for research and blood...
PURPOSE: The Small Animal Radiation Research Platform (SARRP) has been developed for conformal microirradiation with on-board cone beam CT (CBCT) guidance. The graphics processing unit (GPU)-accelerated Superposition-Convolution (SC) method for dose computation has...
Chemotherapy has been successfully used to reduce radiation dose and volume for most pediatric patients. However, because of the failure of chemotherapeutic agents to cross the blood-brain barrier and the lack of response of some brain tumors to these agents,...
Accidental high-dose radiation exposure can result in mortality or severe morbidity through acute radiation syndrome (ARS). The early risk of death from ARS can be attributed mainly to radiation-induced gastrointestinal syndrome (RIGS). Currently, there are no readily...
BACKGROUND: Esophageal cancer is an aggressive disease with poor survival rates. A more patient-tailored approach based on predictive biomarkers could improve outcome. We aimed to predict radiotherapy (RT) response by imaging tumor hypoxia with 18F-FAZA PET/CT in an...
In this study, we investigate the use of multifunctional smart radiotherapy biomaterials (SRBs) loaded with immunoadjuvants for boosting the abscopal effect of local radiotherapy (RT). SRBs were designed similar to currently used inert RT biomaterials, incorporating a...
Radiotherapy is a proven skin cancer treatment modality with cure rates comparable to surgery. To make sure of its effectiveness while being safe, it is necessary to provide conformal dose coverage at the target (tumour) while sparing the surrounding normal tissues....
Radiotherapy remains one of many treatment options available for patients diagnosed with non-melanoma skin cancer (NMSC). NMSC is a radiation-responsive cancer and patients treated with definitive radiotherapy can expect excellent local control rates of >90–95%....
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