Area of Interest: Radiation Research
Preclinical radiation biology has become increasingly sophisticated due to the implementation of advanced small animal image guided radiation platforms into laboratory investigation. The Xstrahl small animal radiation research platform (SARRP) enables state-of-the-art...
For the last 12 years the CIX3 irradiator cabinet has been a stable of cancer research centres around the world. With demand high, Xstrahl spent 2 years developing a new generation of the system, with reduced footprint, safer controls, larger irradiation chamber and...
The aim of this study was to investigate a single crystal diamond detector, the microDiamond detector from PTW (PTW-Freiburg, Freiburg, Germany), concerning the particular requirements in the set-up and energy range used in small animal radiotherapy (RT) research...
Purpose The precise dosimetric and geometric characteristics of small animal irradiators are essential to achieving reproducible dose delivery, especially in cases where image‐guidance is utilized. Currently, radiochromic film is the established measurement tool used...
The goal of this work was to establish imaging dose to mouse organs with a validated Monte Carlo (MC) model of the image-guided Small Animal Radiation Research Platform (SARRP) and to investigate the effect of scatter from the internal walls on animal therapy dose...
Radiation therapy plays a crucial role in the management of breast cancer. However, current standards of care have yet to accommodate patient-specific radiation sensitivity. Raman spectroscopy is promising for applications in radiobiological studies and as a technique...
"The demand for orthovoltage therapy today exceeds the supply," so think the radiologists at the Mariinsky Hospital in St. Petersburg. The X-ray room has been functioning in the Mariinsky Hospital since 1952 and was first equipped with Russian X-ray therapies. In...
Glioblastoma (GBM) is a hyper vascular malignant tumour with a poor prognosis. Despite the availability of current chemotherapy and targeted therapies in GBM, not many therapeutic benefits have been achieved due to GBM developing drug resistance. Most therapies have...
PURPOSE: To implement Velocity-based image fusion and adaptive deformable registration to enable treatment planning for preclinical murine models of fractionated stereotactic radiosurgery (fSRS) using the small animal radiation research platform (SARRP). METHODS AND...
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