Although checkpoint immunotherapies have revolutionized the treatment of cancer, not all tumor types have seen substantial benefit. Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in which very limited responses to immunotherapy have been...
Chemotherapy has been successfully used to reduce radiation dose and volume for most paediatric patients. However, because of the failure of chemotherapeutic agents to cross the blood-brain barrier and the lack of response of some brain tumours to these agents,...
Focus has been given to imaging and high-precision irradiation devices for preclinical tumor model development in recent years. Image-guided radiation therapy (IGRT) including innovative treatment planning techniques comparable to patient treatment can be achieved in...
PURPOSE/OBJECTIVE: Radiotherapy (RT) induces an immunogenic antitumor response, but also some immunosuppressive barriers. It remains unclear how different fractionation protocols can modulate the immune microenvironment. Clinical studies are ongoing to evaluate immune...
Significant improvements in radiotherapy are likely to come from biological rather than technical optimization, for example increasing tumour radiosensitivity via combination with targeted therapies. Such paradigms must first be evaluated in preclinical models for...
In their paper “Effect of X-ray minibeam radiation therapy on clonogenic survival of glioma cells.” Guardiola C, Prezado Y, Roulin C, Bergs JWJ report on the first in vitro study performed in an X-ray Small Animal Radiation Research Platform (SARRP) modified for...
June 14th, 2019 – Xstrahl Medical, global leader in superficial radiotherapy devices to treat non-melanoma skin cancer and dermatological conditions, is spotlighting its RADiant treatment system at the 2019 CalDerm NorCal Conference at the Meritage, Napa Valley, CA....
13th June, 2019 Xstrahl Spotlights Full Range of X-Ray Therapy and Radiation Research Systems at DEGRO 2019, June 13-16th Company also announces launch of patient-focused, German-language website providing information on treatment options for a range of benign...
Radiation exposure is known to cause accelerated aging and damage to the ovary, but the contribution of indirect versus direct effects is not well understood. In their paper “Use of a Small Animal Radiation Research Platform (SARRP) facilitates analysis of systemic...
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