Navigation

X-Rays Minibeam Radiation Therapy at a Conventional Irradiator: Pilot Evaluation in F98-Glioma Bearing Rats and Dose Calculations in a Human Phantom

 In

Извините, этот техт доступен только в “Британский Английский” и “Американский Английский”. For the sake of viewer convenience, the content is shown below in this site default language. You may click one of the links to switch the site language to another available language.

Publication: X-Rays Minibeam Radiation Therapy at a Conventional Irradiator: Pilot Evaluation in F98-Glioma Bearing Rats and Dose Calculations in a Human Phantom

Authors: Sotiropoulos, Marios Brisebard, Elise Le Dudal, Marine Jouvion, Gregory Juchaux, Marjorie Crépin, Delphine Sebrie, Catherine Jourdain, Laurene Labiod, Dalila Lamirault, Charlotte Pouzoulet, Frederic Prezado, Yolanda

Abstract

Minibeam radiation therapy (MBRT) is a type of spatial fractionated radiotherapy that uses submillimetric beams. This work reports on a pilot study on normal tissue response and the increase of the lifespan of glioma-bearing rats when irradiated with a tabletop x-ray system. Our results show a significant widening of the therapeutic window for brain tumours treated with MBRT: an important proportion of long-term survivals (60%) coupled with a significant reduction of toxicity when compared with conventional (broad beam) irradiations. In addition, the clinical translation of the minibeam treatment at a conventional irradiator is evaluated through a possible human head treatment plan.

See the full study

Please fill out your details below to download our brochures. Your only need to do once to unlock access.
Send