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Muriplan, the new pre-clinical treatment planning system for the Xstrahl Small Animal Radiation Research Platform (SARRP).

Specialised Software

Xstrahl have developed a unique dose planning, verification, and treatment delivery system; Muriplan. This intuitive system has been designed to enable researchers to both plan and execute experiments. This fully integrated software will guide the scientist through a step by step process allowing them to carry out the treatment plan in an easy and seamless fashion.

Muriplan has been designed to mimic clinical practice by allowing the investigator to view the 3D reconstructed cone beam-CT image, register/fuse other images like MR and PET/CT, and contour the target as well as surrounding tissue. Furthermore, the capability to save a treatment plan and access it at a later time allows for increased workflow in fractionated treatment schedules. Along with evaluation and validation tools which include isodose lines and the ability to create a dose volume histogram (DVH), Muriplan allows for the control of all hardware components of SARRP included X-ray delivery, imaging, and robotics.

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Pre-Clinical Results to Clinical Practice

Developed in house by Xstrahl, Muriplan allows researchers the versatility to create simple or complex beam arrangements in a clinically relevant way. From single planar static beams to parallel opposed beams, and continuous arc therapies to multiple isocenter treatments. Muriplan enables the ability to execute true non-coplanar beam arrangements, a common clinical practice.

Muriplan is designed to guide the researcher through the treatment planning process in a smooth and consistent manner. Easy to navigate, this treatment planning system is equipped with individual modules for each step to ensure the investigator has completed the necessary steps to proceed further. Although developed to mimic clinical practice, Muriplan’s user friendly design allows researchers from any academic and professional level to use the software successfully.

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Step-by-step guide to the Muriplan Planning System

  1. CT Acquisition – GPU based reconstruction reduces imaging time to 1min
  2. Simple Segmentation into Air, Lung, Fat, Tissue and Bone – Automatic process, can save values for different CT protocols
  3. Contouring – Includes tools for grey scale matching, paint and erase contours
  4. Beam Planning – Set isocenters add beams and arc deliveries. Prescribe dose to each isocenter
  5. Dose Computation – GPU based calculation, 7 sec/beam
  6. Verification – Isodose lines and Dose Volume Histograms
  7. Delivery – Beam cordinates and tretment time automatically loaded into the SARRP, click OK to deliver each beam

For more information about Muriplan get in touch.