Navigation

The Xstrahl CIX2 X-ray irradiator enables safe irradiation of in vitro and in vivo biological samples within a laboratory environment.

CIX2

Meeting the needs of medical and biological research, the CIX2 is a self-contained cabinet incorporating the irradiation chamber and system electronics in one enclosure. The software interface allows for multiple user logins, while X-ray exposures can be programmed and executed automatically. In addition to removing the health and safety burden associated with the use of radioactive sources, the Xstrahl CIX2 provides a safer, simpler and less costly alternative to radioisotope irradiators for radiation exposure studies.

The CIX2 X-ray research irradiator cabinet consists of:

  • Lead shielded irradiation chamber
  • Movable operator control panel with an intuitive touch screen interface
  • Beam hardening filters, which tailor the maximum depth of penetrating X-rays to suit your research
  • Counterbalanced vertical access door, resulting in a smaller footprint and safe, easy access to specimens
Xstrahl-cabinet-9

Research Applications

  • Bystander effects
  • Tumour micro environment
  • Radiobiology studies
  • DNA repair mechanisms
  • Radiosensitisers
  • Abscopal effects
  • Combination therapy studies
  • Bone marrow chimera studies
  • Immunotherapy
  • Hypoxia research
  • Normal tissue toxicity
  • Low dose radiobiology studies
  • Subcutaneous tumour models

For more information about CIX2 X-ray irradiator download our brochure.

Add Ons & Accessories

  • Additional collimators to vary irradiated size area
  • Laser alignment system for easy specimen setup
  • CCTV (camera) for internal observation of irradiation chamber during operation/exposure
  • Hypoxia gas control chamber for in-vitro studies
  • Independent dose measurement systems
  • Specimen turntable option

Bespoke Commissioning

Bespoke commissioning of the cabinet based on your research needs in order to provide the most accurate dosimetry data for your research.

Technical Specification

External: W-110.5cm, D-96cm, H-201cm

Irradiation Chamber: W-57 cm, D-60 cm, H-65 cm

Total Weight: Cabinet: 1,100 kg

Irradiation Table: Manual adjustment of the specimen shelf 20cm to 70cm FSD

Maximum Field Size: 43.5cm circle at 70cm FSD

Tube Voltage: Up to 220 kV

Tube Current: 1.0mA to 30mA

Maximum Power Output: 3 kW (broad focus for designated stability)

Other Products

The Xstrahl CIX2 X-ray irradiator enables safe irradiation of in vitro and in vivo biological samples within a laboratory environment. Check out the rest of our Life Sciences range.

  • Prior to acquisition of the SARRP we were left with an obvious and significant void in our pre-clinical arsenal to investigate existing and novel cancer therapies. The technological similarity of the SARRP with the medical systems in our clinic and availability of ongoing technical support from Xstrahl were decisive factors. The SARRP forms an integral part of our translational research pipeline and will greatly expand the capacity, potential and quality of our cancer and radiation research.

    SARRP Irradiator Manager, Royal North Shore Hospital & Research Director, Bill Walsh Translational Cancer Research, Sydney Vital, Sydney, Australia
  • SARRP has really made a significant impact in our lab, the ability to accurately target small volumes with image guidance hasn’t been possible before and we are now constantly evolving our approaches to leverage the technology to its maximum potential. Clearly our ability to delivery clinically relevant radiotherapy treatments in preclinical models has taken a major step forward, it up to us as a research community to translate this to the next generation of clinical innovatives

    SARRP Lead Lecturer of the Center of Cancer Research and Cell Biology, Leeds Institute of Cancer and Pathology, Queen's University, Belfast, United Kingdom
  • We have been using the CIX2 X-ray cabinet for some years for cell culture experiments, and it is one of the most frequently used machines in our lab. In my opinion, the x-ray irradiator is a great tool for the irradiation of cells in our research lab. The cabinet runs very stable and is easy to operate (even for non-experienced visitors) and offers all options needed for our research making it extremely user-friendly. The possibility to change the filters quickly and to work with different distances away from the x-ray tube markedly enlarges the spectrum of experiments, which can be performed, and the safety aspect is hereby a big advantage. Furthermore, the technical support of X-Strahl is an outstanding example of good customer service.

    CIX2 Postdoctoral Researcher, Ludwig Maximilian University of Munich, Munich, Germany
  • We have found SARRP an extremely valuable resource for pre-clinical work in which we aim to mimic clinical treatment regimens as closely as possible. SARRP enables efficient, accurate and reproducible pre-clinical radiotherapy that is especially valuable for assessing drug-radiation combinations in realistic schedules. We have been very impressed by the user-friendly interface in MuriPlan, which is straightforward for users and  can be interfaced with imaging modalities such as MRI and bioluminescence for optimised image-guided planning. SARRP has become central to our translational pipeline in radiation biology and comes with extremely good support and maintenance to take the stress out of running large pre-clinical experiments.

    SARRP & MuriPlan Professor of Clinical Oncology and Neuro-Oncology, Leeds Institute of Cancer and Pathology, Leeds University, Leeds, United Kingdom
  • The irradiation devices developed by Xstrahl for radiobiological research, both in vitro and in vivo, certainly are of outstanding quality in this field of research. We use the Xstrahl SARRP system successfully for our in-vivo-research on orthotopic small animal tumour models. With this system we are able to mimic the clinical situation and especially irradiation in mice much more precisely and easier than in former times.  So it helps us to make our research more reliable and more clinically relevant. From my point of view, the customer service provided by Xstrahl is close to perfect. All in all, the possibilities provided by Xstrahl's irradiation equipment, e.g to closely mimic the radiotherapeutic clinical routine in small animal models (CT-based treatment planning with the SARRP system) is absolutely outstanding.

    SARRP Postdoctoral Researcher, Ludwig Maximilian University of Munich, Munich, Germany